STK38L Antibody (PACO42594)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO42594
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | STK38L Antibody (PACO42594) |
Antibody SKU: | PACO42594 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Serine/threonine-protein kinase 38-like protein (212-464AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: STK38L antibody at 6µg/ml. Lane 1: A375 whole cell lysate. Lane 2: HepG2 whole cell lysate. Lane 3: A549 whole cell lysate. Lane 4: HCT116 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 55, 44 kDa. Observed band size: 55 kDa. | |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO42594 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO42594 at dilution of 1:100. |
Background: | Involved in the regulation of structural processes in differentiating and mature neuronal cells. |
Synonyms: | Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2), STK38L, KIAA0965 NDR2 |
UniProt Protein Function: | NDR2: a non-receptor S/T kinase of the AGC group. Activated by binding of S100B which releases autoinhibitory N-lobe interactions, enabling ATP to bind followed by autophosphorylation of a serine in the kinase domain. A threonine in the C-terminal domain then undergoes calcium-dependent phosphorylation by an upstream kinase. Interactions between the phosphorylated threonine and the N-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of MOB1/MOBKL1A and MOB2/HCCA2 to the N-terminal of STK38L. May be involved in the regulation of structural processes in neuronal cells. |
UniProt Protein Details: | Protein type:EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); AGC group; NDR family Chromosomal Location of Human Ortholog: 12p11.23 Cellular Component: actin cytoskeleton; cytoplasm Molecular Function:ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity Biological Process: peptidyl-serine phosphorylation; protein amino acid phosphorylation; regulation of cellular component organization and biogenesis |
UniProt Code: | Q9Y2H1 |
NCBI GenInfo Identifier: | 56749668 |
NCBI Gene ID: | 23012 |
NCBI Accession: | Q9Y2H1.3 |
UniProt Secondary Accession: | Q9Y2H1,Q8TBX7, A8K4U0, B4E3J8, |
UniProt Related Accession: | Q9Y2H1 |
Molecular Weight: | 43,170 Da |
NCBI Full Name: | Serine/threonine-protein kinase 38-like |
NCBI Synonym Full Names: | serine/threonine kinase 38 like |
NCBI Official Symbol: | STK38L |
NCBI Official Synonym Symbols: | NDR2 |
NCBI Protein Information: | serine/threonine-protein kinase 38-like |
UniProt Protein Name: | Serine/threonine-protein kinase 38-like |
UniProt Synonym Protein Names: | NDR2 protein kinase; Nuclear Dbf2-related kinase 2 |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | STK38L |
UniProt Entry Name: | ST38L_HUMAN |