STK38 Antibody (PACO12537)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO12537
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | STK38 Antibody (PACO12537) |
Antibody SKU: | PACO12537 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human STK38 |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | serine/threonine kinase 38;STK38;NDR;NDR1 ; |
UniProt Protein Function: | NDR1: is an AGC kinase of the NDR family. An apparent upstream regulator of Myc activity in human B-cell lymphoma. Mediates apoptosis downstream of the tumor suppressor proteins RASSF1A and MST1. Reduced expression of NDR1 results in defective apoptotic responses and a predisposition to develop T cell lymphoma in mice. Activated by binding of S100B which releases autoinhibitory N-lobe interactions. Ubiquitously expressed with highest levels observed in peripheral blood leukocytes. |
UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, AGC; EC 2.7.11.1; AGC group; NDR family Chromosomal Location of Human Ortholog: 6p21 Cellular Component: cytoplasm; nucleus Molecular Function:ATP binding; magnesium ion binding; mitogen-activated protein kinase kinase kinase binding; protein binding; protein serine/threonine kinase activity Biological Process: negative regulation of MAP kinase activity; peptidyl-serine phosphorylation; protein amino acid phosphorylation; protein modification process |
NCBI Summary: | This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
UniProt Code: | Q15208 |
NCBI GenInfo Identifier: | 56749457 |
NCBI Gene ID: | 11329 |
NCBI Accession: | Q15208.1 |
UniProt Secondary Accession: | Q15208,Q503A1, |
UniProt Related Accession: | Q15208 |
Molecular Weight: | 54,190 Da |
NCBI Full Name: | Serine/threonine-protein kinase 38 |
NCBI Synonym Full Names: | serine/threonine kinase 38 |
NCBI Official Symbol: | STK38 |
NCBI Official Synonym Symbols: | NDR; NDR1 |
NCBI Protein Information: | serine/threonine-protein kinase 38 |
UniProt Protein Name: | Serine/threonine-protein kinase 38 |
UniProt Synonym Protein Names: | NDR1 protein kinase; Nuclear Dbf2-related kinase 1 |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | STK38 |
UniProt Entry Name: | STK38_HUMAN |