STK17B Antibody (PACO30178)
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주문- SKU:
- PACO30178
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | STK17B Antibody (PACO30178) |
Antibody SKU: | PACO30178 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Serine/threonine-protein kinase 17B protein (235-366AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot Positive WB detected in: HepG2 whole cell lysate, Mouse brain tissue All lanes: STK17B antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 43 kDa Observed band size: 43 kDa . | |
IHC image of PACO30178 diluted at 1:300 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. |
Synonyms: | Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2), STK17B, DRAK2 |
UniProt Protein Function: | DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.Protein type: EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; DAPK familyChromosomal Location of Human Ortholog: 2q32.3Cellular Component: nucleusMolecular Function: ATP binding; protein kinase activity; protein serine/threonine kinase activityBiological Process: protein amino acid autophosphorylation; protein amino acid phosphorylation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O94768 |
NCBI GenInfo Identifier: | 14423909 |
NCBI Gene ID: | 9262 |
NCBI Accession: | O94768.1 |
UniProt Secondary Accession: | O94768 |
UniProt Related Accession: | O94768 |
Molecular Weight: | 42,344 Da |
NCBI Full Name: | Serine/threonine-protein kinase 17B |
NCBI Synonym Full Names: | serine/threonine kinase 17b |
NCBI Official Symbol: | STK17B |
NCBI Official Synonym Symbols: | DRAK2 |
NCBI Protein Information: | serine/threonine-protein kinase 17B |
UniProt Protein Name: | Serine/threonine-protein kinase 17B |
UniProt Synonym Protein Names: | DAP kinase-related apoptosis-inducing protein kinase 2 |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | STK17B |
UniProt Entry Name: | ST17B_HUMAN |
Antibodies |
STK17B Antibody (PACO06435) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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