ST6GAL1 Antibody (PACO23417)
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주문- SKU:
- PACO23417
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ST6GAL1 Antibody (PACO23417) |
Antibody SKU: | PACO23417 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human ST6GAL1. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from RAW264.7 cells, using ST6GAL1 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using ST6GAL1 antibody. |
Background: | Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. |
Synonyms: | Alpha 2; 6-ST; B-cell antigen CD75; Beta-galactoside alpha-2; 6-sialyltransferase |
UniProt Protein Function: | SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found. |
UniProt Protein Details: | Protein type:EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 3q27.3 Cellular Component: Golgi membrane Molecular Function:beta-galactoside alpha-2,6-sialyltransferase activity; protein binding; sialyltransferase activity Biological Process: humoral immune response; N-acetylneuraminate metabolic process; O-glycan processing; oligosaccharide metabolic process; protein amino acid N-linked glycosylation via asparagine |
NCBI Summary: | This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009] |
UniProt Code: | P15907 |
NCBI GenInfo Identifier: | 115445 |
NCBI Gene ID: | 6480 |
NCBI Accession: | P15907.1 |
UniProt Secondary Accession: | P15907,A8KA14, B2R513, D3DNV3, |
UniProt Related Accession: | P15907 |
Molecular Weight: | 47kDa |
NCBI Full Name: | Beta-galactoside alpha-2,6-sialyltransferase 1 |
NCBI Synonym Full Names: | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
NCBI Official Symbol: | ST6GAL1 |
NCBI Official Synonym Symbols: | ST6N; SIAT1; ST6GalI |
NCBI Protein Information: | beta-galactoside alpha-2,6-sialyltransferase 1 |
UniProt Protein Name: | Beta-galactoside alpha-2,6-sialyltransferase 1 |
UniProt Synonym Protein Names: | B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1 |
Protein Family: | Beta-galactoside alpha-2,6-sialyltransferase |
UniProt Gene Name: | ST6GAL1 |
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