SSX4 Antibody (PACO12484)
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주문- SKU:
- PACO12484
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SSX4 Antibody (PACO12484) |
Antibody SKU: | PACO12484 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Human SSX4 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | synovial sarcoma, X breakpoint 4;SSX4;MGC119056;MGC12411 ; |
UniProt Protein Function: | SSX4: Could act as a modulator of transcription. Belongs to the SSX family. |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: nucleus Molecular Function:transcription corepressor activity |
NCBI Summary: | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60224 |
NCBI GenInfo Identifier: | 6094362 |
NCBI Gene ID: | 548313 |
NCBI Accession: | O60224.1 |
UniProt Secondary Accession: | O60224,Q3SYD4, Q5JQZ0, Q9UJU9, A8MYD4, B2RPE3, |
UniProt Related Accession: | O60224 |
Molecular Weight: | 17,918 Da |
NCBI Full Name: | Protein SSX4 |
NCBI Synonym Full Names: | SSX family member 4B |
NCBI Official Symbol: | SSX4B |
NCBI Official Synonym Symbols: | CT5.4 |
NCBI Protein Information: | protein SSX4 |
UniProt Protein Name: | Protein SSX4 |
UniProt Synonym Protein Names: | Cancer/testis antigen 5.4; CT5.4 |
Protein Family: | Protein |
UniProt Gene Name: | SSX4 |
UniProt Entry Name: | SSX4_HUMAN |