SSRP1 Antibody (PACO12479)
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주문- SKU:
- PACO12479
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SSRP1 Antibody (PACO12479) |
Antibody SKU: | PACO12479 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SSRP1 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | structure specific recognition protein 1;SSRP1;FACT;FACT80;T160 ; |
UniProt Protein Function: | SSRP1: a subunit of the chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. |
UniProt Protein Details: | Protein type:RNA-binding; Nucleolus; Transcription initiation complex; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 11q12 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q08945 |
NCBI GenInfo Identifier: | 730840 |
NCBI Gene ID: | 6749 |
NCBI Accession: | Q08945.1 |
UniProt Secondary Accession: | Q08945,Q5BJG8, |
UniProt Related Accession: | Q08945 |
Molecular Weight: | 81,075 Da |
NCBI Full Name: | FACT complex subunit SSRP1 |
NCBI Synonym Full Names: | structure specific recognition protein 1 |
NCBI Official Symbol: | SSRP1 |
NCBI Official Synonym Symbols: | FACT; T160; FACT80 |
NCBI Protein Information: | FACT complex subunit SSRP1 |
UniProt Protein Name: | FACT complex subunit SSRP1 |
UniProt Synonym Protein Names: | Chromatin-specific transcription elongation factor 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; FACT 80 kDa subunit; FACTp80; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognition protein 1; Structure-specific recognition protein 1; hSSRP1; T160 |
UniProt Gene Name: | SSRP1 |
UniProt Entry Name: | SSRP1_HUMAN |