SPAG5 Antibody (PACO15029)
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주문- SKU:
- PACO15029
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SPAG5 Antibody (PACO15029) |
Antibody SKU: | PACO15029 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human SPAG5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15029(SPAG5 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene. This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |
Synonyms: | sperm associated antigen 5 |
UniProt Protein Function: | SPAG5: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: kinetochore; spindle microtubule Molecular Function:protein binding Biological Process: chromosome segregation; establishment of spindle orientation; mitotic sister chromatid segregation; regulation of attachment of spindle microtubules to kinetochore; spindle organization and biogenesis |
NCBI Summary: | This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96R06 |
NCBI GenInfo Identifier: | 47117278 |
NCBI Gene ID: | 10615 |
NCBI Accession: | Q96R06.2 |
UniProt Secondary Accession: | Q96R06,O95213, Q9BWE8, Q9NT17, Q9UFE6, |
UniProt Related Accession: | Q96R06 |
Molecular Weight: | 134,422 Da |
NCBI Full Name: | Sperm-associated antigen 5 |
NCBI Synonym Full Names: | sperm associated antigen 5 |
NCBI Official Symbol: | SPAG5 |
NCBI Official Synonym Symbols: | MAP126; DEEPEST; hMAP126 |
NCBI Protein Information: | sperm-associated antigen 5 |
UniProt Protein Name: | Sperm-associated antigen 5 |
UniProt Synonym Protein Names: | Astrin; Deepest; Mitotic spindle-associated protein p126; MAP126 |
Protein Family: | Sperm-associated antigen |
UniProt Gene Name: | SPAG5 |
Antibodies | ELISA Kits |
Anti-SPAG5 Antibody (CAB6451) | Human SPAG5(sperm associated antigen 5) ELISA Kit |
SPAG5 Antibody (PACO12413) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |