SNAP29 Antibody (PACO44978)
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주문- SKU:
- PACO44978
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SNAP29 Antibody (PACO44978) |
Antibody SKU: | PACO44978 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Synaptosomal-associated protein 29 protein (1-258AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: SNAP29 antibody at 1.79µg/ml. Lane 1: 293T whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 29 kDa. Observed band size: 29 kDa.. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO44978 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO44978 at dilution of 1:100. |
Background: | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions. |
Synonyms: | Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29), SNAP29 |
UniProt Protein Function: | SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: SNARE complex; centrosome; neuron projection; cytoplasm; plasma membrane; synapse; cell junction Molecular Function:SNAP receptor activity; syntaxin binding Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; exocytosis; autophagic vacuole fusion; vesicle targeting; synaptic vesicle priming Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome |
NCBI Summary: | This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95721 |
NCBI GenInfo Identifier: | 6685982 |
NCBI Gene ID: | 9342 |
NCBI Accession: | O95721.1 |
UniProt Related Accession: | O95721 |
Molecular Weight: | 258 |
NCBI Full Name: | Synaptosomal-associated protein 29 |
NCBI Synonym Full Names: | synaptosomal-associated protein, 29kDa |
NCBI Official Symbol: | SNAP29 |
NCBI Official Synonym Symbols: | CEDNIK; SNAP-29 |
NCBI Protein Information: | synaptosomal-associated protein 29; soluble 29 kDa NSF attachment protein; synaptosomal-associated protein, 29kD; vesicle-membrane fusion protein SNAP-29 |
UniProt Protein Name: | Synaptosomal-associated protein 29 |
UniProt Synonym Protein Names: | Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29 |
Protein Family: | SNAP25 homologous protein |
UniProt Gene Name: | SNAP29 |
UniProt Entry Name: | SNP29_HUMAN |
Antibodies |
Anti-SNAP29 Antibody (CAB4290) |
Anti-SNAP29 Antibody (CAB19952)[KO Validated] |
SNAP29 Antibody (PACO12358) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |