SMYD1 Antibody (PACO43618)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO43618
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SMYD1 Antibody (PACO43618) |
Antibody SKU: | PACO43618 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Histone-lysine N-methyltransferase SMYD1 protein (1-350AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Histone-lysine N-methyltransferase SMYD1 antibody at 2µg/ml. Lane 1: Mouse heart tissue. Lane 2: 293T whole cell lysate. Lane 3: Mouse skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57 kDa. Observed band size: 57 kDa. | |
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO43618 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human lung tissue using PACO43618 at dilution of 1:100. |
Background: | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
Synonyms: | Histone-lysine N-methyltransferase SMYD1 (EC 2.1.1.43) (SET and MYND domain-containing protein 1), SMYD1 |
UniProt Protein Function: | SMYD1: Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
UniProt Protein Details: | Protein type:Methyltransferase, protein lysine; Transcription, coactivator/corepressor; EC 2.1.1.43 Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; DNA binding; metal ion binding; histone-lysine N-methyltransferase activity; transcription corepressor activity Biological Process: chromatin remodeling; transcription, DNA-dependent; heart development; negative regulation of transcription, DNA-dependent; positive regulation of myoblast differentiation |
UniProt Code: | Q8NB12 |
NCBI GenInfo Identifier: | 34925329 |
NCBI Gene ID: | 150572 |
NCBI Accession: | Q8NB12.1 |
UniProt Secondary Accession: | Q8NB12,A0AV30, A6NE13, |
UniProt Related Accession: | Q8NB12 |
Molecular Weight: | 490 |
NCBI Full Name: | Histone-lysine N-methyltransferase SMYD1 |
NCBI Synonym Full Names: | SET and MYND domain containing 1 |
NCBI Official Symbol: | SMYD1 |
NCBI Official Synonym Symbols: | BOP; KMT3D; ZMYND18; ZMYND22 |
NCBI Protein Information: | histone-lysine N-methyltransferase SMYD1; CD8 beta opposite; zinc finger, MYND domain containing 18; SET and MYND domain-containing protein 1 |
UniProt Protein Name: | Histone-lysine N-methyltransferase SMYD1 |
UniProt Synonym Protein Names: | SET and MYND domain-containing protein 1 |
Protein Family: | Histone-lysine N-methyltransferase |
UniProt Gene Name: | SMYD1 |
UniProt Entry Name: | SMYD1_HUMAN |