SLPI Antibody (PACO32336)
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주문- SKU:
- PACO32336
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLPI Antibody (PACO32336) |
Antibody SKU: | PACO32336 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Antileukoproteinase protein (26-132AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO32336 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO32336 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO32336 at dilution of 1:100. |
Background: | acid, stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues. |
Synonyms: | Antileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4), SLPI, WAP4 WFDC4 |
UniProt Protein Function: | SLPI: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues. |
UniProt Protein Details: | Protein type:Secreted; Inhibitor; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q12 Cellular Component: extracellular matrix; extracellular space Molecular Function:endopeptidase inhibitor activity; enzyme binding; protein binding; serine-type endopeptidase inhibitor activity Biological Process: antibacterial humoral response; immune response; innate immune response; negative regulation of protein binding; negative regulation of viral genome replication; response to lipopolysaccharide |
NCBI Summary: | This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014] |
UniProt Code: | P03973 |
NCBI GenInfo Identifier: | 113636 |
NCBI Gene ID: | 6590 |
NCBI Accession: | P03973.2 |
UniProt Secondary Accession: | P03973,P07757, B2R5H8, |
UniProt Related Accession: | P03973 |
Molecular Weight: | 14,326 Da |
NCBI Full Name: | Antileukoproteinase |
NCBI Synonym Full Names: | secretory leukocyte peptidase inhibitor |
NCBI Official Symbol: | SLPI |
NCBI Official Synonym Symbols: | ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I |
NCBI Protein Information: | antileukoproteinase |
UniProt Protein Name: | Antileukoproteinase |
UniProt Synonym Protein Names: | BLPI; HUSI-1 |
Protein Family: | Antileukoproteinase |
UniProt Gene Name: | SLPI |
UniProt Entry Name: | SLPI_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |