SLC7A1 Antibody (PACO57980)
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주문- SKU:
- PACO57980
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC7A1 Antibody (PACO57980) |
Antibody SKU: | PACO57980 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:500-1:1000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human High affinity cationic amino acid, transporter 1 protein (430-492AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO57980 diluted at 1:500 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
Immunofluorescence staining of HepG2 cells with PACO57980 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
IHC image of PACO57980 diluted at 1:500 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | High-affinity, low capacity permease involved in the transport of the cationic amino acid, (arginine, lysine and ornithine) in non-hepatic tissues. |
Synonyms: | High affinity cationic amino acid, transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid, transporter), SLC7A1, ATRC1 ERR REC1L |
UniProt Protein Function: | SLC7A1: High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family Chromosomal Location of Human Ortholog: 13q12.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:arginine transmembrane transporter activity Biological Process: transport; amino acid transport; arginine transport; ion transport; transmembrane transport |
UniProt Code: | P30825 |
NCBI GenInfo Identifier: | 1706185 |
NCBI Gene ID: | 6541 |
NCBI Accession: | P30825.1 |
UniProt Secondary Accession: | P30825,Q5JR50, |
UniProt Related Accession: | P30825 |
Molecular Weight: | |
NCBI Full Name: | High affinity cationic amino acid transporter 1 |
NCBI Synonym Full Names: | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
NCBI Official Symbol: | SLC7A1 |
NCBI Official Synonym Symbols: | ERR; ATRC1; CAT-1; HCAT1; REC1L |
NCBI Protein Information: | high affinity cationic amino acid transporter 1; CAT1; ecotropic retroviral receptor; solute carrier family 7 member 1; amino acid transporter, cationic 1; ecotropic retrovirus receptor homolog; system Y+ basic amino acid transporter; ecotropic retroviral leukemia receptor homolog |
UniProt Protein Name: | High affinity cationic amino acid transporter 1 |
UniProt Synonym Protein Names: | Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; ERR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter |
Protein Family: | High affinity cationic amino acid transporter |
UniProt Gene Name: | SLC7A1 |
UniProt Entry Name: | CTR1_HUMAN |