SLC6A11 Antibody (PACO05084)
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주문- SKU:
- PACO05084
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC6A11 Antibody (PACO05084) |
Antibody SKU: | PACO05084 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the Internal region of human GABA T-3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | SLC6A11; GABT3; GAT3; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11 |
UniProt Protein Function: | SLC6A11: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 3p25.3 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:gamma-aminobutyric acid:sodium symporter activity; transporter activity Biological Process: transport |
NCBI Summary: | The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
UniProt Code: | P48066 |
NCBI GenInfo Identifier: | 1352531 |
NCBI Gene ID: | 6538 |
NCBI Accession: | P48066.1 |
UniProt Secondary Accession: | P48066,Q8IYC9, B2R6U6, |
UniProt Related Accession: | P48066 |
Molecular Weight: | 71kDa |
NCBI Full Name: | Sodium- and chloride-dependent GABA transporter 3 |
NCBI Synonym Full Names: | solute carrier family 6 member 11 |
NCBI Official Symbol: | SLC6A11 |
NCBI Official Synonym Symbols: | GAT3; GAT4; GAT-3 |
NCBI Protein Information: | sodium- and chloride-dependent GABA transporter 3 |
UniProt Protein Name: | Sodium- and chloride-dependent GABA transporter 3 |
UniProt Synonym Protein Names: | Solute carrier family 6 member 11 |
Protein Family: | Sodium- and chloride-dependent GABA transporter |
UniProt Gene Name: | SLC6A11 |