SLC2A5 Antibody (PACO18003)
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주문- SKU:
- PACO18003
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC2A5 Antibody (PACO18003) |
Antibody SKU: | PACO18003 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human SLC2A5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18003(SLC2A5 Antibody) at dilution 1/12, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18003(SLC2A5 Antibody) at dilution 1/12, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. In humans the GLUT5 protein is encoded by the SLC2A5 gene. |
Synonyms: | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
UniProt Protein Function: | GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.2 Cellular Component: apical plasma membrane; integral to plasma membrane; plasma membrane; sarcolemma Molecular Function:fructose transmembrane transporter activity; glucose transmembrane transporter activity Biological Process: carbohydrate metabolic process; fructose transport; glucose transport; hexose transport; regulation of systemic arterial blood pressure mediated by a chemical signal; response to fructose stimulus |
UniProt Code: | P22732 |
NCBI GenInfo Identifier: | 121764 |
NCBI Gene ID: | 6518 |
NCBI Accession: | P22732.1 |
UniProt Secondary Accession: | P22732,Q14770, Q5T977, Q8IVB3, |
UniProt Related Accession: | P22732 |
Molecular Weight: | 26,519 Da |
NCBI Full Name: | Solute carrier family 2, facilitated glucose transporter member 5 |
NCBI Synonym Full Names: | solute carrier family 2 member 5 |
NCBI Official Symbol: | SLC2A5 |
NCBI Official Synonym Symbols: | GLUT5; GLUT-5 |
NCBI Protein Information: | solute carrier family 2, facilitated glucose transporter member 5 |
UniProt Protein Name: | Solute carrier family 2, facilitated glucose transporter member 5 |
UniProt Synonym Protein Names: | Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 |
UniProt Gene Name: | SLC2A5 |
UniProt Entry Name: | GTR5_HUMAN |