SLC25A38 Antibody (PACO39290)
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주문- SKU:
- PACO39290
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC25A38 Antibody (PACO39290) |
Antibody SKU: | PACO39290 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Mitochondrial glycine transporter protein (1-30AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of MCF-7 cells using PACO39290 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane. |
Synonyms: | Mitochondrial glycine transporter (Mitochondrial glycine transporter GlyC) (Solute carrier family 25 member 38), SLC25A38 |
UniProt Protein Function: | SLC25A3: Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD). MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life. Belongs to the mitochondrial carrier family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Mitochondrial; Transporter Chromosomal Location of Human Ortholog: 12q23 Cellular Component: membrane; mitochondrion; integral to plasma membrane; mitochondrial inner membrane Molecular Function:phosphate carrier activity; symporter activity; protein complex binding Biological Process: generation of precursor metabolites and energy; transport Disease: Mitochondrial Phosphate Carrier Deficiency |
NCBI Summary: | This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia (anemia, sideroblastic, 2, pyridoxine-refractory). A related pseudogene is found on chromosome 1. [provided by RefSeq, Aug 2017] |
UniProt Code: | Q96DW6 |
NCBI GenInfo Identifier: | 157388925 |
NCBI Gene ID: | 54977 |
NCBI Accession: | NP_060345 |
UniProt Secondary Accession: | Q96DW6,Q96DW6, |
UniProt Related Accession: | Q96DW6 |
Molecular Weight: | 33kDa |
NCBI Full Name: | mitochondrial glycine transporter isoform 1 |
NCBI Synonym Full Names: | solute carrier family 25 member 38 |
NCBI Official Symbol: | SLC25A38 |
NCBI Official Synonym Symbols: | SIDBA2 |
NCBI Protein Information: | mitochondrial glycine transporter |
UniProt Protein Name: | Phosphate carrier protein, mitochondrial |
UniProt Synonym Protein Names: | Phosphate transport protein; PTP; Solute carrier family 25 member 3 |
UniProt Gene Name: | SLC25A3 |
UniProt Entry Name: | MPCP_HUMAN |
Antibodies |
Anti-SLC25A38 Antibody (CAB13218) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |