SLC25A12 Antibody (PACO06260)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO06260
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC25A12 Antibody (PACO06260) |
Antibody SKU: | PACO06260 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from the Internal region of human ARALAR. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of various cells using ARALAR Polyclonal Antibody. | |
Western Blot analysis of HEPG2 cells using ARALAR Polyclonal Antibody. |
Synonyms: | SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12 |
UniProt Protein Function: | SLC25A12: Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle. Defects in SLC25A12 are the cause of global cerebral hypomyelination (GCHM). A disorder with onset in infancy and characterized by severe psychomotor retardation, hypotonia, seizures, hypomyelination of the central nervous system, with the gray matter appearing relatively unaffected. Belongs to the mitochondrial carrier family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion Molecular Function:acidic amino acid transmembrane transporter activity; calcium ion binding; L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity Biological Process: aspartate transport; gluconeogenesis; L-glutamate transport; malate-aspartate shuttle; response to calcium ion Disease: Hypomyelination, Global Cerebral |
NCBI Summary: | This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012] |
UniProt Code: | O75746 |
NCBI GenInfo Identifier: | 206729858 |
NCBI Gene ID: | 8604 |
NCBI Accession: | O75746.2 |
UniProt Secondary Accession: | O75746,Q96AM8, B3KR64, |
UniProt Related Accession: | O75746 |
Molecular Weight: | 75kDa |
NCBI Full Name: | Calcium-binding mitochondrial carrier protein Aralar1 |
NCBI Synonym Full Names: | solute carrier family 25 member 12 |
NCBI Official Symbol: | SLC25A12 |
NCBI Official Synonym Symbols: | AGC1; ARALAR; EIEE39 |
NCBI Protein Information: | calcium-binding mitochondrial carrier protein Aralar1 |
UniProt Protein Name: | Calcium-binding mitochondrial carrier protein Aralar1 |
UniProt Synonym Protein Names: | Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12 |
UniProt Gene Name: | SLC25A12 |
Antibodies | ELISA Kits |
Anti-SLC25A12 Antibody (CAB11688) | Human SLC25A12 / Aralar1 ELISA Kit |
Human Calcium-binding mitochondrial carrier protein Aralar1 (SLC25A12) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |