SLC25A11 Antibody (PACO14999)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO14999
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC25A11 Antibody (PACO14999) |
Antibody SKU: | PACO14999 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human SLC25A11 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO14999(SLC25A11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: PACO14999(SLC25A11 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14999(SLC25A11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acid, , and plays an important role in several metabolic processes, contains the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. |
Synonyms: | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 |
UniProt Protein Function: | SLC25A11: Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Belongs to the mitochondrial carrier family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 17p13.2 Cellular Component: integral to plasma membrane; mitochondrial inner membrane; mitochondrion; nucleus Molecular Function:oxoglutarate:malate antiporter activity Biological Process: gluconeogenesis; glucose metabolic process; transport |
NCBI Summary: | The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011] |
UniProt Code: | Q02978 |
NCBI GenInfo Identifier: | 21361114 |
NCBI Gene ID: | 8402 |
NCBI Accession: | NP_003553.2 |
UniProt Secondary Accession: | Q02978,O75537, Q969P7, F5GY65, |
UniProt Related Accession: | Q02978 |
Molecular Weight: | 37.8kDa |
NCBI Full Name: | mitochondrial 2-oxoglutarate/malate carrier protein isoform 1 |
NCBI Synonym Full Names: | solute carrier family 25 member 11 |
NCBI Official Symbol: | SLC25A11 |
NCBI Official Synonym Symbols: | OGC; SLC20A4 |
NCBI Protein Information: | mitochondrial 2-oxoglutarate/malate carrier protein |
UniProt Protein Name: | Mitochondrial 2-oxoglutarate/malate carrier protein |
UniProt Synonym Protein Names: | Solute carrier family 25 member 11 |
UniProt Gene Name: | SLC25A11 |