SLC22A3 Antibody (PACO18898)
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주문- SKU:
- PACO18898
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC22A3 Antibody (PACO18898) |
Antibody SKU: | PACO18898 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human SLC22A3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO18898(SLC22A3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: PACO18898(SLC22A3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18898(SLC22A3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. |
Synonyms: | Solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
UniProt Protein Function: | SLC22A3: Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; toxin transporter activity; organic cation transmembrane transporter activity; dopamine transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity Biological Process: dopamine transport; organic cation transport; histamine uptake; quaternary ammonium group transport; regulation of appetite; multidrug transport; transmembrane transport |
NCBI Summary: | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75751 |
NCBI GenInfo Identifier: | 11415038 |
NCBI Gene ID: | 6581 |
NCBI Accession: | NP_068812.1 |
UniProt Related Accession: | O75751 |
Molecular Weight: | |
NCBI Full Name: | solute carrier family 22 member 3 |
NCBI Synonym Full Names: | solute carrier family 22 member 3 |
NCBI Official Symbol: | SLC22A3 |
NCBI Official Synonym Symbols: | EMT; EMTH; OCT3 |
NCBI Protein Information: | solute carrier family 22 member 3 |
UniProt Protein Name: | Solute carrier family 22 member 3 |
UniProt Synonym Protein Names: | Extraneuronal monoamine transporter; EMT; Organic cation transporter 3 |
UniProt Gene Name: | SLC22A3 |
UniProt Entry Name: | S22A3_HUMAN |