SLC16A7 Antibody (PACO18205)
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주문- SKU:
- PACO18205
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC16A7 Antibody (PACO18205) |
Antibody SKU: | PACO18205 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:15-1:50 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human SLC16A7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18205(SLC16A7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: A549 cells, Primary antibody: PACO18205(SLC16A7 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18205(SLC16A7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. |
Synonyms: | solute carrier family 16, member 7 (monocarboxylic acid, transporter 2) |
UniProt Protein Function: | SLC16A7: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q13 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:pyruvate secondary active transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity; pyruvate transmembrane transporter activity Biological Process: transmembrane transport |
NCBI Summary: | This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
UniProt Code: | O60669 |
NCBI GenInfo Identifier: | 313104141 |
NCBI Gene ID: | 9194 |
NCBI Accession: | O60669.2 |
UniProt Related Accession: | O60669 |
Molecular Weight: | |
NCBI Full Name: | Monocarboxylate transporter 2 |
NCBI Synonym Full Names: | solute carrier family 16 member 7 |
NCBI Official Symbol: | SLC16A7 |
NCBI Official Synonym Symbols: | MCT2 |
NCBI Protein Information: | monocarboxylate transporter 2 |
UniProt Protein Name: | Monocarboxylate transporter 2 |
UniProt Synonym Protein Names: | Solute carrier family 16 member 7 |
Protein Family: | Molybdate transporter |
UniProt Gene Name: | SLC16A7 |
UniProt Entry Name: | MOT2_HUMAN |
Antibodies | ELISA Kits |
Anti-SLC16A7 Antibody (CAB12386) | Human Monocarboxylate transporter 2 (SLC16A7) ELISA Kit |
Anti-SLC16A7 Antibody (CAB3015) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |