SLC12A7 Antibody (PACO52910)
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주문- SKU:
- PACO52910
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC12A7 Antibody (PACO52910) |
Antibody SKU: | PACO52910 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Solute carrier family 12 member 7 protein (11-117AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO52910 at dilution of 1:100. | |
Immunofluorescent analysis of A549 cells using PACO52910 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO52910 at dilution of 1:100. |
Background: | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acid, fication (By similarity). |
Synonyms: | Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4), SLC12A7, KCC4 |
UniProt Protein Function: | KCC4: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. Belongs to the SLC12A transporter family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: plasma membrane Molecular Function:potassium ion symporter activity; potassium:chloride symporter activity; protein kinase binding Biological Process: ion transport; synaptic transmission; transport |
UniProt Code: | Q9Y666 |
NCBI GenInfo Identifier: | 166202480 |
NCBI Gene ID: | 10723 |
NCBI Accession: | Q9Y666.3 |
UniProt Secondary Accession: | Q9Y666,Q4G0F3, Q96I81, Q9H7I3, Q9H7I7, Q9UFW2, A6NDS8 |
UniProt Related Accession: | Q9Y666 |
Molecular Weight: | Calculated MW: 28kDa/119kDaObserved MW: 119kDa |
NCBI Full Name: | Solute carrier family 12 member 7 |
NCBI Synonym Full Names: | solute carrier family 12 member 7 |
NCBI Official Symbol: | SLC12A7 |
NCBI Official Synonym Symbols: | KCC4 |
NCBI Protein Information: | solute carrier family 12 member 7 |
UniProt Protein Name: | Solute carrier family 12 member 7 |
UniProt Synonym Protein Names: | Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4 |
Protein Family: | Solute carrier family |
UniProt Gene Name: | SLC12A7 |
Antibodies |
Anti-SLC12A7 Antibody (CAB12299) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |