SIRT3 Antibody (PACO43376)
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주문- SKU:
- PACO43376
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SIRT3 Antibody (PACO43376) |
Antibody SKU: | PACO43376 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human NAD-dependent protein deacetylase sirtuin-3, mitochondrial protein (20-130AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: NAD-dependent protein deacetylase sirtuin-3, mitochondrial antibody at 1µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 44, 29 kDa. Observed band size: 44 kDa. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43376 at dilution of 1:100. | |
Western Blot. Positive WB detected in: HepG2 whole cell lysate. All lanes: SIRT3 antibody at 0.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44, 29 kDa. Observed band size: 44 kDa. |
Background: | NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. |
Synonyms: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3), SIRT3, SIR2L3 |
UniProt Code: | Q9NTG7 |
NCBI GenInfo Identifier: | 38258651 |
NCBI Gene ID: | 23410 |
NCBI Accession: | Q9NTG7.2 |
UniProt Secondary Accession: | Q9NTG7,Q9Y6E8, B7Z5U6, |
UniProt Related Accession: | Q9NTG7 |
Molecular Weight: | 399 |
NCBI Full Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
NCBI Synonym Full Names: | sirtuin 3 |
NCBI Official Symbol: | SIRT3 |
NCBI Official Synonym Symbols: | SIR2L3 |
NCBI Protein Information: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial; sir2-like 3; sirtuin type 3; SIR2-like protein 3; regulatory protein SIR2 homolog 3; NAD-dependent deacetylase sirtuin-3, mitochondrial; silent mating type information regulation 2, S.cerevisiae, homolog 3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase |
UniProt Protein Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
UniProt Synonym Protein Names: | Regulatory protein SIR2 homolog 3; SIR2-like protein 3 |
Protein Family: | NAD-dependent protein deacetylase sirtuin |
UniProt Gene Name: | SIRT3 |
UniProt Entry Name: | SIR3_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |