SETBP1 Antibody (PACO42754)
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주문- SKU:
- PACO42754
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SETBP1 Antibody (PACO42754) |
Antibody SKU: | PACO42754 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human SET-binding protein (1-242AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | SET-binding protein (SEB), SETBP1, KIAA0437 |
UniProt Protein Function: | SETBP1: Defects in SETBP1 are the cause of Schinzel-Giedion midface retraction syndrome (SGMFS). It is a disorder characterized by severe mental retardation, distinctive facial features, and multiple congenital malformations including skeletal abnormalities, genitourinary and renal malformations, cardiac defects, as well as a higher-than-normal prevalence of tumors, notably neuroepithelial neoplasia. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: nucleus Molecular Function:DNA binding Disease: Mental Retardation, Autosomal Dominant 29; Schinzel-giedion Midface Retraction Syndrome |
NCBI Summary: | This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q9Y6X0 |
NCBI GenInfo Identifier: | 294862494 |
NCBI Gene ID: | 26040 |
NCBI Accession: | Q9Y6X0.3 |
UniProt Secondary Accession: | Q9Y6X0,Q6P6C3, Q9UEF3, A6H8W5, |
UniProt Related Accession: | Q9Y6X0 |
Molecular Weight: | Calculated MW: 26kDa/175kDaObserved MW: 175kDa |
NCBI Full Name: | SET-binding protein |
NCBI Synonym Full Names: | SET binding protein 1 |
NCBI Official Symbol: | SETBP1 |
NCBI Official Synonym Symbols: | SEB; MRD29 |
NCBI Protein Information: | SET-binding protein |
UniProt Protein Name: | SET-binding protein |
Protein Family: | SET-binding protein |
UniProt Gene Name: | SETBP1 |
UniProt Entry Name: | SETBP_HUMAN |