SERPINB5 Antibody (PACO43590)
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주문- SKU:
- PACO43590
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SERPINB5 Antibody (PACO43590) |
Antibody SKU: | PACO43590 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Serpin B5 protein (21-189AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Serpin B5 antibody at 2µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43, 26 kDa. Observed band size: 43 kDa. | |
Immunohistochemistry of paraffin-embedded human cervical cancer using PACO43590 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43590 at dilution of 1:100. |
Background: | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
Synonyms: | Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5), SERPINB5, PI5 |
UniProt Protein Function: | maspin: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Interacts with IRF6. Normal mammary epithelial cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.33 Cellular Component: extracellular space; cytoplasm Molecular Function:serine-type endopeptidase inhibitor activity; protein binding Biological Process: extracellular matrix organization and biogenesis; morphogenesis of an epithelium; cell motility; regulation of epithelial cell proliferation |
UniProt Code: | P36952 |
NCBI GenInfo Identifier: | 229462757 |
NCBI Gene ID: | 5268 |
NCBI Accession: | P36952.2 |
UniProt Secondary Accession: | P36952,Q6N0B4, Q8WW89, B2R6Y4, |
UniProt Related Accession: | P36952 |
Molecular Weight: | 25,763 Da |
NCBI Full Name: | Serpin B5 |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
NCBI Official Symbol: | SERPINB5 |
NCBI Official Synonym Symbols: | PI5; maspin |
NCBI Protein Information: | serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 |
UniProt Protein Name: | Serpin B5 |
UniProt Synonym Protein Names: | Maspin; Peptidase inhibitor 5; PI-5 |
Protein Family: | Serpin |
UniProt Gene Name: | SERPINB5 |
UniProt Entry Name: | SPB5_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |