SERPINA9 Antibody (PACO19225)
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주문- SKU:
- PACO19225
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SERPINA9 Antibody (PACO19225) |
Antibody SKU: | PACO19225 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human SERPINA9 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19225(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, 231 cells, U937 cells, Raji cells, Primary antibody: PACO19225(SERPINA9 Antibody) at dilution 1/337.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19225(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Serpin A9 also known as centerin or GCET1 is a protein that in humans is encoded by the SERPINA9 gene located on chromosome 14q32.1.[1] Serpin A9 is a member of the serpin family of serine protease inhibitors. The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases. Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. |
Synonyms: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 |
UniProt Protein Function: | SERPINA9: Protease inhibitor that inhibits trypsin and trypsin- like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). Belongs to the serpin family. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Inhibitor; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 14q32.13 Cellular Component: extracellular space Molecular Function:serine-type endopeptidase inhibitor activity |
UniProt Code: | Q86WD7 |
NCBI GenInfo Identifier: | 215274213 |
NCBI Gene ID: | 327657 |
NCBI Accession: | Q86WD7.3 |
UniProt Secondary Accession: | Q86WD7,Q2T9J2, Q6UWP9, Q86WD4, Q86WD5, Q86WD6, Q86YP6 Q86YP7, B4DVH4, B9ZVX3, |
UniProt Related Accession: | Q86WD7 |
Molecular Weight: | 48,610 Da |
NCBI Full Name: | Serpin A9 |
NCBI Synonym Full Names: | serpin family A member 9 |
NCBI Official Symbol: | SERPINA9 |
NCBI Official Synonym Symbols: | GCET1; SERPINA11; SERPINA11b |
NCBI Protein Information: | serpin A9 |
UniProt Protein Name: | Serpin A9 |
UniProt Synonym Protein Names: | Centerin; Germinal center B-cell-expressed transcript 1 protein |
Protein Family: | Serpin |
UniProt Gene Name: | SERPINA9 |
UniProt Entry Name: | SPA9_HUMAN |