SERPINA12 Antibody (PACO17076)
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주문- SKU:
- PACO17076
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SERPINA12 Antibody (PACO17076) |
Antibody SKU: | PACO17076 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human SERPINA12 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17076(SERPINA12 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO17076(SERPINA12 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
Synonyms: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
UniProt Protein Function: | SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family. |
UniProt Protein Details: | Protein type:Inhibitor; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 14q32.13 Cellular Component: extracellular space; plasma membrane Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: positive regulation of phosphoinositide 3-kinase cascade; negative regulation of lipid biosynthetic process; negative regulation of gluconeogenesis; positive regulation of insulin receptor signaling pathway |
UniProt Code: | Q8IW75 |
NCBI GenInfo Identifier: | 74728144 |
NCBI Gene ID: | 145264 |
NCBI Accession: | Q8IW75.1 |
UniProt Related Accession: | Q8IW75 |
Molecular Weight: | 47,175 Da |
NCBI Full Name: | Serpin A12 |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
NCBI Official Symbol: | SERPINA12 |
NCBI Official Synonym Symbols: | OL-64 |
NCBI Protein Information: | serpin A12; vaspin; visceral adipose-specific SERPIN; visceral adipose tissue-derived serine protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 |
UniProt Protein Name: | Serpin A12 |
UniProt Synonym Protein Names: | OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin |
Protein Family: | Serpin |
UniProt Gene Name: | SERPINA12 |
UniProt Entry Name: | SPA12_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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