SDC1 Antibody (PACO43255)
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주문- SKU:
- PACO43255
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SDC1 Antibody (PACO43255) |
Antibody SKU: | PACO43255 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Syndecan-1 protein (25-240AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO43255 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43255 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO43255 at dilution of 1:100. |
Background: | Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. |
Synonyms: | Syndecan-1 (SYND1) (CD antigen CD138), SDC1, SDC |
UniProt Protein Function: | syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Extracellular matrix Chromosomal Location of Human Ortholog: 2p24.1 Cellular Component: cell surface; cytoplasm; focal adhesion; Golgi lumen; integral to plasma membrane; lysosomal lumen; plasma membrane Molecular Function:protein binding; protein C-terminus binding Biological Process: cell migration; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; lipoprotein metabolic process; myoblast development; retinoid metabolic process; striated muscle cell development |
NCBI Summary: | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | P18827 |
NCBI GenInfo Identifier: | 229463011 |
NCBI Gene ID: | 6382 |
NCBI Accession: | P18827.3 |
UniProt Secondary Accession: | P18827,Q53QV0, Q546D3, Q96HB7, D6W523, |
UniProt Related Accession: | P18827,AAB21434,AAB23935 |
Molecular Weight: | 32,462 Da |
NCBI Full Name: | Syndecan-1 |
NCBI Synonym Full Names: | syndecan 1 |
NCBI Official Symbol: | SDC1 |
NCBI Official Synonym Symbols: | SDC; CD138; SYND1; syndecan |
NCBI Protein Information: | syndecan-1 |
UniProt Protein Name: | Syndecan-1 |
UniProt Synonym Protein Names: | CD_antigen: CD138 |
Protein Family: | COMPASS component |
UniProt Gene Name: | SDC1 |
UniProt Entry Name: | SDC1_HUMAN |
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