SCD Antibody (PACO49038)
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주문- SKU:
- PACO49038
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SCD Antibody (PACO49038) |
Antibody SKU: | PACO49038 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Acyl-CoA desaturase protein (10-70AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO49038 at dilution of 1:100. |
Background: | Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acid,. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid, oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). |
Synonyms: | Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid, desaturase) (Stearoyl-CoA desaturase) (hSCD1), SCD |
UniProt Protein Function: | SCD: Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Belongs to the fatty acid desaturase family. |
UniProt Protein Details: | Protein type:EC 1.14.19.1; Endoplasmic reticulum; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase Chromosomal Location of Human Ortholog: 10q24.31 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane; nucleolus Molecular Function:iron ion binding; oxidoreductase activity; stearoyl-CoA 9-desaturase activity Biological Process: unsaturated fatty acid biosynthetic process |
NCBI Summary: | This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015] |
UniProt Code: | O00767 |
NCBI GenInfo Identifier: | 21431730 |
NCBI Gene ID: | 6319 |
NCBI Accession: | O00767.2 |
UniProt Secondary Accession: | O00767,Q16150, Q53GR9, Q5W037, Q5W038, Q6GSS4, Q96KF6 Q9BS07, Q9Y695, B2R5U0, D3DR68, |
UniProt Related Accession: | O00767 |
Molecular Weight: | 41,523 Da |
NCBI Full Name: | Acyl-CoA desaturase |
NCBI Synonym Full Names: | stearoyl-CoA desaturase |
NCBI Official Symbol: | SCD |
NCBI Official Synonym Symbols: | SCD1; FADS5; SCDOS; hSCD1; MSTP008 |
NCBI Protein Information: | acyl-CoA desaturase |
UniProt Protein Name: | Acyl-CoA desaturase |
UniProt Synonym Protein Names: | Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase |
Protein Family: | Acyl-CoA desaturase |
UniProt Gene Name: | SCD |
Antibodies | ELISA Kits |
Anti-SCD Antibody (CAB16429)[KO Validated] | Human Acyl-CoA desaturase(delta-9-desaturase) ELISA Kit |
Human Acyl-CoA desaturase (SCD) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |