S1PR5 Antibody (PACO19013)
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주문- SKU:
- PACO19013
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | S1PR5 Antibody (PACO19013) |
Antibody SKU: | PACO19013 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human S1PR5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human brain malignant glioma tissue, MCF7 cells, Primary antibody: PACO19013(S1PR5 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
Background: | The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid, (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors are S1P receptors; others are LPA receptors. |
Synonyms: | Sphingosine-1-phosphate receptor 5 |
UniProt Protein Function: | EDG8: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to membrane; plasma membrane Biological Process: regulation of neuron differentiation |
NCBI Summary: | The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9H228 |
NCBI GenInfo Identifier: | 62510663 |
NCBI Gene ID: | 53637 |
NCBI Accession: | Q9H228.1 |
UniProt Secondary Accession: | Q9H228,Q6NW11, |
UniProt Related Accession: | Q9H228 |
Molecular Weight: | 398 |
NCBI Full Name: | Sphingosine 1-phosphate receptor 5 |
NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 5 |
NCBI Official Symbol: | S1PR5 |
NCBI Official Synonym Symbols: | EDG8; S1P5; Edg-8; SPPR-1; SPPR-2 |
NCBI Protein Information: | sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-pr |
UniProt Protein Name: | Sphingosine 1-phosphate receptor 5 |
UniProt Synonym Protein Names: | Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8 |
UniProt Gene Name: | S1PR5 |
UniProt Entry Name: | S1PR5_HUMAN |
Antibodies | ELISA Kits |
S1PR5 Antibody (PACO04617) | Human S1PR5 / EDG8 ELISA Kit |
S1PR5 Antibody (PACO12014) | Human Sphingosine 1-phosphate receptor 5 (S1PR5) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |