S100A11 Antibody (PACO29684)
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주문- SKU:
- PACO29684
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | S100A11 Antibody (PACO29684) |
Antibody SKU: | PACO29684 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein S100-A11 protein (2-105AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO29684 at dilution of 1:100. |
Background: | Facilitates the differentiation and the cornification of keratinocytes. |
Synonyms: | Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed], S100A11, MLN70 S100C |
UniProt Protein Function: | S100A11: a calcium-binding regulatory protein of the S-100 family. Interacts with the N-termini of annexins A1. May regulate fusion processes such as endo- and exocytosis. Increases in the early stage of pancreatic carcinogenesis and decreases during subsequent progression to cancer. Increased expression in anaplastic large cell lymphoma. |
UniProt Protein Details: | Protein type:Calcium-binding; DNA replication; Cell cycle regulation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; extracellular space; nucleus; ruffle Molecular Function:calcium-dependent protein binding; protein binding; protein homodimerization activity Biological Process: negative regulation of cell proliferation; negative regulation of DNA replication; signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P31949 |
NCBI GenInfo Identifier: | 1710818 |
NCBI Gene ID: | 6282 |
NCBI Accession: | P31949.2 |
UniProt Secondary Accession: | P31949,Q5VTK0, |
UniProt Related Accession: | P31949 |
Molecular Weight: | 11,740 Da |
NCBI Full Name: | Protein S100-A11 |
NCBI Synonym Full Names: | S100 calcium binding protein A11 |
NCBI Official Symbol: | S100A11 |
NCBI Official Synonym Symbols: | MLN70; S100C; HEL-S-43 |
NCBI Protein Information: | protein S100-A11 |
UniProt Protein Name: | Protein S100-A11 |
UniProt Synonym Protein Names: | Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70 |
Protein Family: | Protein |
UniProt Gene Name: | S100A11 |
UniProt Entry Name: | S10AB_HUMAN |
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