RPP38 Antibody (PACO62163)
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주문- SKU:
- PACO62163
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RPP38 Antibody (PACO62163) |
Antibody SKU: | PACO62163 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ribonuclease P protein subunit p38 protein (210-283AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO62163 diluted at 1:400 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO62163 diluted at 1:400 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus. |
Synonyms: | Ribonuclease P protein subunit p38 (RNaseP protein p38) (EC 3.1.26.5), RPP38 |
UniProt Protein Function: | RPP38: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus. Belongs to the ribosomal protein L7Ae family. |
UniProt Protein Details: | Protein type:Nucleolus; Ribonuclease; EC 3.1.26.5 Chromosomal Location of Human Ortholog: 10p13 Cellular Component: nucleolar ribonuclease P complex; nucleolus; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: rRNA processing; tRNA 5'-leader removal |
UniProt Code: | P78345 |
NCBI GenInfo Identifier: | 83305638 |
NCBI Gene ID: | 10557 |
NCBI Accession: | P78345.2 |
UniProt Secondary Accession: | P78345,Q53F71, Q8NHS8, B3KPY0, D3DRT8, |
UniProt Related Accession: | P78345 |
Molecular Weight: | 31,834 Da |
NCBI Full Name: | Ribonuclease P protein subunit p38 |
NCBI Synonym Full Names: | ribonuclease P/MRP subunit p38 |
NCBI Official Symbol: | RPP38 |
NCBI Protein Information: | ribonuclease P protein subunit p38 |
UniProt Protein Name: | Ribonuclease P protein subunit p38 |
Protein Family: | Ribonuclease P protein |
UniProt Gene Name: | RPP38 |
UniProt Entry Name: | RPP38_HUMAN |