RND3 Antibody (PACO47618)
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주문- SKU:
- PACO47618
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RND3 Antibody (PACO47618) |
Antibody SKU: | PACO47618 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO47618 at dilution of 1:100. |
Background: | Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. |
Synonyms: | Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3), RND3, ARHE RHO8 RHOE |
UniProt Protein Function: | RhoE: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family. |
UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rho; G protein; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q23.3 Cellular Component: Golgi membrane; focal adhesion Molecular Function:GTPase activity; protein binding; GTP binding Biological Process: metabolic process; small GTPase mediated signal transduction; cell adhesion; actin cytoskeleton organization and biogenesis |
NCBI Summary: | This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011] |
UniProt Code: | P61587 |
NCBI GenInfo Identifier: | 47606459 |
NCBI Gene ID: | 390 |
NCBI Accession: | P61587.1 |
UniProt Secondary Accession: | P61587,P52199, D3DP95, |
UniProt Related Accession: | P61587 |
Molecular Weight: | 244 |
NCBI Full Name: | Rho-related GTP-binding protein RhoE |
NCBI Synonym Full Names: | Rho family GTPase 3 |
NCBI Official Symbol: | RND3 |
NCBI Official Synonym Symbols: | ARHE; Rho8; RhoE; memB |
NCBI Protein Information: | rho-related GTP-binding protein RhoE; protein MemB; small GTP binding protein Rho8; ras homolog gene family, member E; rho-related GTP-binding protein Rho8 |
UniProt Protein Name: | Rho-related GTP-binding protein RhoE |
UniProt Synonym Protein Names: | Protein MemB; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3 |
Protein Family: | Rho-related GTP-binding protein |
UniProt Gene Name: | RND3 |
UniProt Entry Name: | RND3_HUMAN |