RHOBTB2 Antibody (PACO19547)
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주문- SKU:
- PACO19547
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RHOBTB2 Antibody (PACO19547) |
Antibody SKU: | PACO19547 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human RHOBTB2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19547(RHOBTB2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19547(RHOBTB2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | Rho-related BTB domain containing 2 |
UniProt Protein Function: | RHOBTB2: is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rho; G protein, monomeric Chromosomal Location of Human Ortholog: 8p21.3 Cellular Component: plasma membrane; cytosol Molecular Function:GTP binding Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction |
NCBI Summary: | The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9BYZ6 |
NCBI GenInfo Identifier: | 12667516 |
NCBI Gene ID: | 23221 |
NCBI Accession: | AAG61157.1 |
UniProt Secondary Accession: | Q9BYZ6,O94825, Q8N4A8, Q9BZK6, A8K9Z8, D3DSR8, E9PBU2 E9PEI7, |
UniProt Related Accession: | Q9BYZ6 |
Molecular Weight: | 83,469 Da |
NCBI Full Name: | DBC2 |
NCBI Synonym Full Names: | Rho-related BTB domain containing 2 |
NCBI Official Symbol: | RHOBTB2 |
NCBI Official Synonym Symbols: | DBC2 |
NCBI Protein Information: | rho-related BTB domain-containing protein 2; deleted in breast cancer 2 gene protein; p83 |
UniProt Protein Name: | Rho-related BTB domain-containing protein 2 |
UniProt Synonym Protein Names: | Deleted in breast cancer 2 gene protein; p83 |
UniProt Gene Name: | RHOBTB2 |
UniProt Entry Name: | RHBT2_HUMAN |
Antibodies |
Anti-RHOBTB2 Antibody (CAB18432) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |