RHD Antibody (PACO46166)
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주문- SKU:
- PACO46166
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RHD Antibody (PACO46166) |
Antibody SKU: | PACO46166 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Blood group Rh(D) polypeptide protein (32-76AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse liver tissue. All lanes: RHD antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 46, 35, 54, 44, 42 kDa. Observed band size: 46 kDa.. | |
Immunofluorescent analysis of A549 cells using PACO46166 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO46166 at dilution of 1:100. |
Background: | May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. |
Synonyms: | Blood group Rh(D) polypeptide (RHXIII) (Rh polypeptide 2) (RhPII) (Rhesus D antigen) (CD antigen CD240D), RHD |
UniProt Protein Function: | RHD: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: integral to plasma membrane Molecular Function:ammonium transmembrane transporter activity Biological Process: nitrogen utilization; organic cation transport |
NCBI Summary: | The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02161 |
NCBI GenInfo Identifier: | 296452980 |
NCBI Gene ID: | 6007 |
NCBI Accession: | Q02161.3 |
UniProt Secondary Accession: | Q02161,Q02162, Q07618, Q16147, Q16235, Q16355, Q5VSK0 Q5XLS9, Q5XLT1, Q5XLT2, Q9NPK0, Q9UQ20, |
UniProt Related Accession: | Q02161 |
Molecular Weight: | 41,694 Da |
NCBI Full Name: | Blood group Rh(D) polypeptide |
NCBI Synonym Full Names: | Rh blood group D antigen |
NCBI Official Symbol: | RHD |
NCBI Official Synonym Symbols: | RH; Rh4; RH30; RhII; RhPI; DIIIc; RHCED; RHDel; RHPII; RhDCw; CD240D; RHXIII; RHDVA(TT); RhK562-II |
NCBI Protein Information: | blood group Rh(D) polypeptide |
UniProt Protein Name: | Blood group Rh(D) polypeptide |
UniProt Synonym Protein Names: | RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD_antigen: CD240D |
UniProt Gene Name: | RHD |
UniProt Entry Name: | RHD_HUMAN |