RETNLB Antibody (PACO14957)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO14957
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RETNLB Antibody (PACO14957) |
Antibody SKU: | PACO14957 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human RETNLB |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14957(RETNLB Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14957(RETNLB Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Resistin-like β is a protein that in humans is encoded by the RETNLB gene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action. |
Synonyms: | resistin like beta |
UniProt Protein Function: | resistin-like beta: Probable hormone. Belongs to the resistin/FIZZ family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q13.1 Cellular Component: cellular_component; extracellular region Molecular Function:hormone activity; molecular_function Biological Process: cell proliferation |
UniProt Code: | Q9BQ08 |
NCBI GenInfo Identifier: | 14211897 |
NCBI Gene ID: | 84666 |
NCBI Accession: | NP_115968.1 |
UniProt Secondary Accession: | Q9BQ08,Q14D27, |
UniProt Related Accession: | Q9BQ08 |
Molecular Weight: | 11,730 Da |
NCBI Full Name: | resistin-like beta |
NCBI Synonym Full Names: | resistin like beta |
NCBI Official Symbol: | RETNLB |
NCBI Official Synonym Symbols: | XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta |
NCBI Protein Information: | resistin-like beta; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cyste |
UniProt Protein Name: | Resistin-like beta |
UniProt Synonym Protein Names: | Colon and small intestine-specific cysteine-rich protein; Colon carcinoma-related gene protein; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; RELMbeta |
Protein Family: | Resistin |
UniProt Gene Name: | RETNLB |
UniProt Entry Name: | RETNB_HUMAN |