RDH11 Antibody (PACO16960)
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주문- SKU:
- PACO16960
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RDH11 Antibody (PACO16960) |
Antibody SKU: | PACO16960 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human RDH11 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO16960(RDH11 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. |
Synonyms: | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
UniProt Protein Function: | RDH11: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; EC 1.1.1.300 Chromosomal Location of Human Ortholog: 14q24.1 Cellular Component: endoplasmic reticulum membrane; photoreceptor inner segment; integral to membrane; intracellular Molecular Function:retinol dehydrogenase activity Biological Process: phototransduction, visible light; retinal metabolic process; retinol metabolic process; adaptation of rhodopsin mediated signaling; retinoid metabolic process Disease: Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome |
NCBI Summary: | The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q8TC12 |
NCBI GenInfo Identifier: | 90110515 |
NCBI Gene ID: | 51109 |
NCBI Accession: | ABD90542.1 |
UniProt Secondary Accession: | Q8TC12,Q6IAH5, Q9NRW0, Q9Y391, A6NDK3, A8K062, B2RB26 B4DDW0, |
UniProt Related Accession: | Q8TC12 |
Molecular Weight: | 35,386 Da |
NCBI Full Name: | retinol dehydrogenase 11, partial |
NCBI Synonym Full Names: | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
NCBI Official Symbol: | RDH11 |
NCBI Official Synonym Symbols: | MDT1; CGI82; PSDR1; RALR1; SCALD; ARSDR1; HCBP12; SDR7C1 |
NCBI Protein Information: | retinol dehydrogenase 11; retinal reductase 1; HCV core-binding protein HCBP12; prostate short-chain dehydrogenase reductase 1; prostate short-chain dehydrogenase/reductase 1; short chain dehydrogenase/reductase family 7C, member 1; androgen-regulated short-chain dehydrogenase/reductase 1 |
UniProt Protein Name: | Retinol dehydrogenase 11 |
UniProt Synonym Protein Names: | Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1 |
Protein Family: | Retinol dehydrogenase |
UniProt Gene Name: | RDH11 |
UniProt Entry Name: | RDH11_HUMAN |
Antibodies | ELISA Kits |
Anti-RDH11 Antibody (CAB18454) | Human RDH11 (Retinol dehydrogenase 11)ELISA Kit (HUFI06863) |
RDH11 Antibody (PACO11785) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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