RASSF6 Antibody (PACO22548)
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주문- SKU:
- PACO22548
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RASSF6 Antibody (PACO22548) |
Antibody SKU: | PACO22548 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human RASSF6. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HeLa cells, using RASSF6 antibody. |
Background: | Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B By similarity. |
Synonyms: | Ras association domain-containing protein 6; |
UniProt Protein Function: | RASSF6: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q13.3 Molecular Function:protein binding Biological Process: apoptosis; positive regulation of apoptosis; signal transduction |
NCBI Summary: | This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q6ZTQ3 |
NCBI GenInfo Identifier: | 74749658 |
NCBI Gene ID: | 166824 |
NCBI Accession: | Q6ZTQ3.1 |
UniProt Secondary Accession: | Q6ZTQ3,Q68DT2, Q6PDA6, Q86WG9, Q86WH0, |
UniProt Related Accession: | Q6ZTQ3 |
Molecular Weight: | 369 |
NCBI Full Name: | Ras association domain-containing protein 6 |
NCBI Synonym Full Names: | Ras association (RalGDS/AF-6) domain family member 6 |
NCBI Official Symbol: | RASSF6 |
NCBI Protein Information: | ras association domain-containing protein 6; putative RAS binding protein; Ras association (RalGDS/AF-6) domain family 6 |
UniProt Protein Name: | Ras association domain-containing protein 6 |
Protein Family: | Ras association domain-containing protein |
UniProt Gene Name: | RASSF6 |
UniProt Entry Name: | RASF6_HUMAN |
Antibodies |
Anti-RASSF6 Antibody (CAB14163) |
Anti-RASSF6 Antibody (CAB5187) |
RASSF6 Antibody (PACO01413) |
RASSF6 Antibody (PACO11736) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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