RAB1B Antibody (PACO49294)
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주문- SKU:
- PACO49294
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | RAB1B Antibody (PACO49294) |
Antibody SKU: | PACO49294 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ras-related protein Rab-1B protein (130-201AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of U251 cells using PACO49294 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. |
Synonyms: | Ras-related protein Rab-1B, RAB1B |
UniProt Protein Function: | RAB1B: Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 11q12 Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; mitochondrion; pre-autophagosomal structure membrane; ER-Golgi intermediate compartment Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding Biological Process: intracellular protein transport; ER to Golgi vesicle-mediated transport; autophagy; virus assembly; Rab protein signal transduction |
NCBI Summary: | Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009] |
UniProt Code: | Q9H0U4 |
NCBI GenInfo Identifier: | 23396834 |
NCBI Gene ID: | 81876 |
NCBI Accession: | Q9H0U4.1 |
UniProt Secondary Accession: | Q9H0U4,A8K7S1, |
UniProt Related Accession: | Q9H0U4 |
Molecular Weight: | 201 |
NCBI Full Name: | Ras-related protein Rab-1B |
NCBI Synonym Full Names: | RAB1B, member RAS oncogene family |
NCBI Official Symbol: | RAB1B |
NCBI Protein Information: | ras-related protein Rab-1B; small GTP-binding protein |
UniProt Protein Name: | Ras-related protein Rab-1B |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB1B |
UniProt Entry Name: | RAB1B_HUMAN |
Antibodies |
Anti-RAB1B Antibody (CAB7514) |
Anti-RAB1B Antibody (CAB19935)[KO Validated] |
RAB1B Antibody (PACO05431) |
RAB1B Antibody (PACO11637) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |