RAB10 Antibody (PACO29304)
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주문- SKU:
- PACO29304
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | RAB10 Antibody (PACO29304) |
Antibody SKU: | PACO29304 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ras-related protein Rab-10 protein (1-196AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO29304 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human glioma using PACO29304 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO29304 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
Synonyms: | Ras-related protein Rab-10, RAB10 |
UniProt Protein Function: | RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor. |
UniProt Protein Details: | Protein type:G protein, monomeric; G protein; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: Golgi apparatus; phagocytic vesicle membrane; endoplasmic reticulum membrane; recycling endosome; cytoplasmic vesicle membrane; focal adhesion; recycling endosome membrane; exocyst; plasma membrane; endosome membrane; trans-Golgi network; endosome Molecular Function:GTPase activity; GDP binding; GTP binding; myosin V binding Biological Process: metabolic process; establishment of neuroblast polarity; protein secretion; endosome transport; regulation of exocytosis; vesicle-mediated transport; polarized epithelial cell differentiation; intracellular protein transport; Golgi to plasma membrane transport; antigen processing and presentation; cellular response to insulin stimulus; axonogenesis; Golgi to plasma membrane protein transport; Rab protein signal transduction; vesicle docking during exocytosis |
NCBI Summary: | RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009] |
UniProt Code: | P61026 |
NCBI GenInfo Identifier: | 46577638 |
NCBI Gene ID: | 10890 |
NCBI Accession: | P61026.1 |
UniProt Related Accession: | P61026 |
Molecular Weight: | 22.5kDa |
NCBI Full Name: | Ras-related protein Rab-10 |
NCBI Synonym Full Names: | RAB10, member RAS oncogene family |
NCBI Official Symbol: | RAB10 |
NCBI Protein Information: | ras-related protein Rab-10 |
UniProt Protein Name: | Ras-related protein Rab-10 |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB10 |
UniProt Entry Name: | RAB10_HUMAN |
Antibodies | ELISA Kits |
Anti-RAB10 Antibody (CAB4459) | Human RAB10 ELISA Kit |
RAB10 Antibody (PACO11629) | Human Ras-related protein Rab-10 (RAB10) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |