PTGER2 Antibody (PACO20277)
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주문- SKU:
- PACO20277
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PTGER2 Antibody (PACO20277) |
Antibody SKU: | PACO20277 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human PTGER2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20277(PTGER2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Mouse liver tissue, Mouse lung tissue, Primary antibody: PACO20277(PTGER2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20277(PTGER2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid, which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. |
Synonyms: | prostaglandin E receptor 2 (subtype EP2), 53kDa |
UniProt Protein Function: | PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q22 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:prostaglandin E receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation; response to lipopolysaccharide; response to progesterone stimulus Disease: Asthma, Nasal Polyps, And Aspirin Intolerance |
NCBI Summary: | This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009] |
UniProt Code: | P43116 |
NCBI GenInfo Identifier: | 38258920 |
NCBI Gene ID: | 5732 |
NCBI Accession: | P43116.2 |
UniProt Secondary Accession: | P43116,Q52LG8, D3DSC0, |
UniProt Related Accession: | P43116 |
Molecular Weight: | 39,761 Da |
NCBI Full Name: | Prostaglandin E2 receptor EP2 subtype |
NCBI Synonym Full Names: | prostaglandin E receptor 2 |
NCBI Official Symbol: | PTGER2 |
NCBI Official Synonym Symbols: | EP2 |
NCBI Protein Information: | prostaglandin E2 receptor EP2 subtype |
UniProt Protein Name: | Prostaglandin E2 receptor EP2 subtype |
UniProt Synonym Protein Names: | Prostanoid EP2 receptor |
Protein Family: | Prostaglandin E2 receptor |
UniProt Gene Name: | PTGER2 |
UniProt Entry Name: | PE2R2_HUMAN |
Antibodies | ELISA Kits |
Anti-PTGER2 Antibody (CAB2914) | Human EP2 (Prostaglandin E Receptor 2 ) CLIA Kit (HUES01017) |
Anti-PTGER2 Antibody (CAB9053) | |
PTGER2 Antibody (PACO03037) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |