PTDSS1 Antibody (PACO31832)
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주문- SKU:
- PACO31832
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PTDSS1 Antibody (PACO31832) |
Antibody SKU: | PACO31832 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: PTDSS1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 56, 39, 35 kDa Observed band size: 35 kDa . | |
Immunofluorescent analysis of HepG2 cells using PACO31832 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO31832 at dilution of 1:100. |
Background: | Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. |
Synonyms: | Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I), PTDSS1, KIAA0024 PSSA |
UniProt Protein Function: | PTDSS1: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. Belongs to the phosphatidyl serine synthase family. |
UniProt Protein Details: | Protein type:EC 2.7.8.29; Membrane protein, integral; Mitochondrial; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Transferase Chromosomal Location of Human Ortholog: 8q22 Cellular Component: endoplasmic reticulum membrane; integral to membrane; membrane Molecular Function:transferase activity Biological Process: phosphatidylserine biosynthetic process; phospholipid biosynthetic process Disease: Lenz-majewski Hyperostotic Dwarfism |
NCBI Summary: | The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014] |
UniProt Code: | P48651 |
NCBI GenInfo Identifier: | 1346881 |
NCBI Gene ID: | 9791 |
NCBI Accession: | P48651.1 |
UniProt Secondary Accession: | P48651,Q9BUQ5, B4DE85, E5RFC5, |
UniProt Related Accession: | P48651 |
Molecular Weight: | 34,579 Da |
NCBI Full Name: | Phosphatidylserine synthase 1 |
NCBI Synonym Full Names: | phosphatidylserine synthase 1 |
NCBI Official Symbol: | PTDSS1 |
NCBI Official Synonym Symbols: | LMHD; PSS1; PSSA |
NCBI Protein Information: | phosphatidylserine synthase 1 |
UniProt Protein Name: | Phosphatidylserine synthase 1 |
UniProt Synonym Protein Names: | Serine-exchange enzyme I |
Protein Family: | Phosphatidylserine synthase |
UniProt Gene Name: | PTDSS1 |
UniProt Entry Name: | PTSS1_HUMAN |
Antibodies |
Anti-PTDSS1 Antibody (CAB13065) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |