PPT2 Antibody (PACO64483)
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주문- SKU:
- PACO64483
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PPT2 Antibody (PACO64483) |
Antibody SKU: | PACO64483 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | IF:1:100-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Lysosomal thioesterase PPT2 protein (28-302AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of MCF-7 cells with PACO64483 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid, followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. |
Synonyms: | Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2) (S-thioesterase G14), PPT2 |
UniProt Protein Function: | PPT2: Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins. Belongs to the palmitoyl-protein thioesterase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.2.-; Hydrolase; Lipid Metabolism - fatty acid elongation in mitochondria Chromosomal Location of Human Ortholog: 6p21.32 Cellular Component: lysosomal lumen |
NCBI Summary: | This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene. [provided by RefSeq, Feb 2011] |
UniProt Code: | Q9UMR5 |
NCBI GenInfo Identifier: | 296453016 |
NCBI Gene ID: | 9374 |
NCBI Accession: | Q9UMR5.4 |
UniProt Secondary Accession: | Q9UMR5,O14799, Q0P6K0, A2ABC9, A2ABD1, A2ARM7, A2BFH7 A2BFH9, A2BFI2, A8K9L4, B0S868, G8JLE1, |
UniProt Related Accession: | Q9UMR5 |
Molecular Weight: | 34kDa |
NCBI Full Name: | Lysosomal thioesterase PPT2 |
NCBI Synonym Full Names: | palmitoyl-protein thioesterase 2 |
NCBI Official Symbol: | PPT2 |
NCBI Official Synonym Symbols: | G14; PPT-2; C6orf8 |
NCBI Protein Information: | lysosomal thioesterase PPT2 |
UniProt Protein Name: | Lysosomal thioesterase PPT2 |
UniProt Synonym Protein Names: | S-thioesterase G14 |
Protein Family: | Phosphoenolpyruvate/phosphate translocator |
UniProt Gene Name: | PPT2 |
Antibodies |
Anti-PPT2 Antibody (CAB12251) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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