POP4 Antibody (PACO45162)
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주문- SKU:
- PACO45162
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | POP4 Antibody (PACO45162) |
Antibody SKU: | PACO45162 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ribonuclease P protein subunit p29 protein (1-220AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO45162 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45162 at dilution of 1:100. |
Background: | Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. |
Synonyms: | Ribonuclease P protein subunit p29 (hPOP4) (EC 3.1.26.5), POP4, RPP29 |
UniProt Protein Function: | POP4: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. Belongs to the eukaryotic/archaeal RNase P protein component 1 family. |
UniProt Protein Details: | Protein type:EC 3.1.26.5; Nucleolus; RNA processing; RNA-binding; Ribonuclease Chromosomal Location of Human Ortholog: 19q12 Cellular Component: nucleoplasm; ribonuclease MRP complex; ribonuclease P complex Molecular Function:protein binding; ribonuclease MRP activity; ribonuclease P activity; ribonuclease P RNA binding; RNA binding Biological Process: rRNA processing; tRNA 5'-leader removal; tRNA processing |
NCBI Summary: | This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] |
UniProt Code: | O95707 |
NCBI GenInfo Identifier: | 20141663 |
NCBI Gene ID: | 10775 |
NCBI Accession: | O95707.2 |
UniProt Secondary Accession: | O95707,Q5XKL7, Q6FHW9, Q9UQQ3, |
UniProt Related Accession: | O95707 |
Molecular Weight: | 25kDa |
NCBI Full Name: | Ribonuclease P protein subunit p29 |
NCBI Synonym Full Names: | POP4 homolog, ribonuclease P/MRP subunit |
NCBI Official Symbol: | POP4 |
NCBI Official Synonym Symbols: | RPP29 |
NCBI Protein Information: | ribonuclease P protein subunit p29 |
UniProt Protein Name: | Ribonuclease P protein subunit p29 |
Protein Family: | RNases |
UniProt Gene Name: | POP4 |