PLXNB1 Antibody (PACO20251)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO20251
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | PLXNB1 Antibody (PACO20251) |
Antibody SKU: | PACO20251 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human PLXNB1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20251(PLXNB1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20251(PLXNB1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. |
Synonyms: | plexin B1 |
UniProt Protein Function: | PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc.; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; intracellular Molecular Function:protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding Biological Process: positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; axon guidance; cell migration; positive regulation of axonogenesis; negative regulation of osteoblast proliferation; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis |
UniProt Code: | O43157 |
NCBI GenInfo Identifier: | 194272180 |
NCBI Gene ID: | 5364 |
NCBI Accession: | NP_001123554.1 |
UniProt Secondary Accession: | O43157,Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93, A6H8Y2, |
UniProt Related Accession: | O43157 |
Molecular Weight: | 232,298 Da |
NCBI Full Name: | plexin-B1 |
NCBI Synonym Full Names: | plexin B1 |
NCBI Official Symbol: | PLXNB1 |
NCBI Official Synonym Symbols: | SEP; PLXN5; KIAA0407; MGC149167; PLEXIN-B1 |
NCBI Protein Information: | plexin-B1; plexin 5; OTTHUMP00000164806; OTTHUMP00000210032; OTTHUMP00000210033; semaphorin receptor SEP |
UniProt Protein Name: | Plexin-B1 |
UniProt Synonym Protein Names: | Semaphorin receptor SEP |
Protein Family: | Plexin |
UniProt Gene Name: | PLXNB1 |
UniProt Entry Name: | PLXB1_HUMAN |