PLIN2 Antibody (PACO19312)
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주문- SKU:
- PACO19312
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PLIN2 Antibody (PACO19312) |
Antibody SKU: | PACO19312 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human PLIN2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19312(PLIN2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: PACO19312(PLIN2 Antibody) at dilution 1/680, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19312(PLIN2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. |
Synonyms: | perilipin 2 |
UniProt Protein Function: | perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family. |
UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 9p22.1 Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane; lipid particle; nucleus; cytosol Biological Process: long-chain fatty acid transport; response to drug; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance |
NCBI Summary: | The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011] |
UniProt Code: | Q99541 |
NCBI GenInfo Identifier: | 34577059 |
NCBI Gene ID: | 123 |
NCBI Accession: | NP_001113.2 |
UniProt Secondary Accession: | Q99541,Q9BSC3, |
UniProt Related Accession: | Q99541 |
Molecular Weight: | 48,075 Da |
NCBI Full Name: | perilipin-2 |
NCBI Synonym Full Names: | perilipin 2 |
NCBI Official Symbol: | PLIN2 |
NCBI Official Synonym Symbols: | ADFP; ADRP |
NCBI Protein Information: | perilipin-2; adipophilin; adipose differentiation-related protein |
UniProt Protein Name: | Perilipin-2 |
UniProt Synonym Protein Names: | Adipophilin; Adipose differentiation-related protein; ADRP |
UniProt Gene Name: | PLIN2 |
UniProt Entry Name: | PLIN2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |