PLCB3 Antibody (PACO20240)
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주문- SKU:
- PACO20240
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PLCB3 Antibody (PACO20240) |
Antibody SKU: | PACO20240 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human PLCB3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20240(PLCB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane 1-4: PC3 cells, A431 cells, mouse lung tissue, Hela cells, Primary antibody: PACO20240(PLCB3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20240(PLCB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the phosphoinositide phospholipase C β enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants. |
Synonyms: | phospholipase C, β 3 |
UniProt Protein Function: | PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate. |
UniProt Protein Details: | Protein type:Phospholipase; EC 3.1.4.11; Carbohydrate Metabolism - inositol phosphate Chromosomal Location of Human Ortholog: 11q13 Cellular Component: cytosol; nucleoplasm; protein complex; sarcolemma Molecular Function:calcium ion binding; calmodulin binding; phosphoinositide phospholipase C activity; phospholipase C activity; signal transducer activity Biological Process: G-protein coupled receptor protein signaling pathway; inositol phosphate metabolic process; lipid catabolic process; post-Golgi vesicle-mediated transport; regulation of systemic arterial blood pressure; synaptic transmission |
NCBI Summary: | This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
UniProt Code: | Q01970 |
NCBI GenInfo Identifier: | 1730573 |
NCBI Gene ID: | 5331 |
NCBI Accession: | Q01970.2 |
UniProt Secondary Accession: | Q01970,Q8N1A4, A5PKZ6, G5E960, |
UniProt Related Accession: | Q01970 |
Molecular Weight: | 131,205 Da |
NCBI Full Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 |
NCBI Synonym Full Names: | phospholipase C beta 3 |
NCBI Official Symbol: | PLCB3 |
NCBI Protein Information: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 |
UniProt Protein Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 |
UniProt Synonym Protein Names: | Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3 |
Protein Family: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase |
UniProt Gene Name: | PLCB3 |
UniProt Entry Name: | PLCB3_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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