Phospho-TK1 (Ser13) Antibody (PACO23947)
- SKU:
- PACO23947
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | Phospho-TK1 (Ser13) Antibody (PACO23947) |
Antibody SKU: | PACO23947 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
Species Reactivity: | Human, Mouse, Rat, Monkey |
Immunogen: | Peptide sequence around phosphorylation site of Serine 13(P-G-S(p)-P-S) derived from Human TK. |
Form: | Liquid |
Storage Buffer: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from COS-7 cells using TK (Phospho-Ser13) Antibody.The lane on the right is treated with the antigen-specific peptide. |
Background: | TK is a cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. |
Synonyms: | TK2 |
UniProt Protein Function: | TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. |
UniProt Protein Details: | Protein type:EC 2.7.1.21; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine; Kinase, other Chromosomal Location of Human Ortholog: 17q23.2-q25.3 Cellular Component: cytosol Molecular Function:identical protein binding; nucleoside kinase activity; zinc ion binding; thymidine kinase activity; ATP binding Biological Process: response to nutrient levels; skeletal muscle cell proliferation; nucleobase, nucleoside and nucleotide metabolic process; response to toxin; liver development; protein homotetramerization; fetal process involved in parturition; deoxyribonucleoside monophosphate biosynthetic process; response to cortisol stimulus; pyrimidine base metabolic process; gut development; response to copper ion; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; thymidine metabolic process; pyrimidine nucleoside salvage; phosphorylation |
UniProt Code: | P04183 |
NCBI GenInfo Identifier: | 23503074 |
NCBI Gene ID: | 7083 |
NCBI Accession: | P04183.2 |
UniProt Secondary Accession: | P04183,Q969V0, Q9UMG9, B2RC58, |
UniProt Related Accession: | P04183 |
Molecular Weight: | 234 |
NCBI Full Name: | Thymidine kinase, cytosolic |
NCBI Synonym Full Names: | thymidine kinase 1, soluble |
NCBI Official Symbol: | TK1 |
NCBI Official Synonym Symbols: | TK2 |
NCBI Protein Information: | thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform |
UniProt Protein Name: | Thymidine kinase, cytosolic |
Protein Family: | Thymidine kinase |
UniProt Gene Name: | TK1 |
UniProt Entry Name: | KITH_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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