Phospho-TENC1 (Y483) Antibody (PACO06961)
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주문- SKU:
- PACO06961
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-TENC1 (Y483) Antibody (PACO06961) |
Antibody SKU: | PACO06961 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from human Tensin-2 around the phosphorylation site of Y483. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of A549 NIH-3T3 SH-SY5Y K562 HELA cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody. | |
Western Blot analysis of 3T3 cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody. |
Synonyms: | TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2 |
UniProt Protein Function: | tensin 2: Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulation; Phosphatase; EC 3.1.3.-; Cell adhesionChromosomal Location of Human Ortholog: 12q13.13Cellular Component: focal adhesion; intracellular; plasma membraneMolecular Function: kinase binding; metal ion binding; phosphoprotein phosphatase activity; protein bindingBiological Process: cellular homeostasis; collagen metabolic process; kidney development; multicellular organism growth; multicellular organismal homeostasis; negative regulation of cell proliferation; protein amino acid dephosphorylation; response to muscle activity |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q63HR2 |
NCBI GenInfo Identifier: | 150416153 |
NCBI Gene ID: | 23371 |
NCBI Accession: | Q63HR2.2 |
UniProt Secondary Accession: | Q63HR2,Q2NL80, Q76MW6, Q7Z5T9, Q8NFF9, Q8NFG0, Q96P25 Q9NT29, A2VDF2, A2VDF3 |
UniProt Related Accession: | Q63HR2 |
Molecular Weight: | 152,452 Da |
NCBI Full Name: | Tensin-2 |
NCBI Synonym Full Names: | tensin 2 |
NCBI Official Symbol: | TNS2 |
NCBI Official Synonym Symbols: | C1TEN; TENC1; C1-TEN |
NCBI Protein Information: | tensin-2 |
UniProt Protein Name: | Tensin-2 |
UniProt Synonym Protein Names: | C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-like C1 domain-containing phosphatase |
Protein Family: | |
UniProt Gene Name: | TNS2 |
UniProt Entry Name: | TNS2_HUMAN |
Antibodies |
TENC1 Antibody (PACO07196) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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