Phospho-RGS16 (Y168) Antibody (PACO04921)
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주문- SKU:
- PACO04921
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Reactivity:
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-RGS16 (Y168) Antibody |
Antibody SKU: | PACO04921 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat, Monkey |
Immunogen: | synthesized peptide derived from human RGS16 around the phosphorylation site of Y168. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | RGS16; RGSR; Regulator of G-protein signaling 16; RGS16; A28-RGS14P; Retinal-specific RGS; RGS-r; hRGS-r; Retinally abundant regulator of G-protein signaling |
UniProt Protein Function: | RGS1: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q31 Cellular Component: cytoplasm; plasma membrane Molecular Function:calmodulin binding; GTPase activator activity Biological Process: immune response; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; positive regulation of GTPase activity |
NCBI Summary: | This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15492 |
NCBI GenInfo Identifier: | 115387108 |
NCBI Gene ID: | 5996 |
NCBI Accession: | NP_002913.3 |
UniProt Secondary Accession: | O15492,O15492, P97428, P56700, |
UniProt Related Accession: | Q08116 |
Molecular Weight: | 23,858 Da |
NCBI Full Name: | regulator of G-protein signaling 1 |
NCBI Synonym Full Names: | regulator of G-protein signaling 1 |
NCBI Official Symbol: | RGS1 |
NCBI Official Synonym Symbols: | 1R20; BL34; IER1; IR20 |
NCBI Protein Information: | regulator of G-protein signaling 1; early response protein 1R20; B-cell activation protein BL34; regulator of G-protein signalling 1; immediate-early response 1, B-cell specific |
UniProt Protein Name: | Regulator of G-protein signaling 1 |
UniProt Synonym Protein Names: | B-cell activation protein BL34; Early response protein 1R20 |
Protein Family: | Regulator of G-protein signaling |
UniProt Gene Name: | RGS1 |
UniProt Entry Name: | RGS1_HUMAN |