Phospho-KCNC4 (S15) Antibody (PACO05963)
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주문- SKU:
- PACO05963
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-KCNC4 (S15) Antibody (PACO05963) |
Antibody SKU: | PACO05963 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:5000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from human Kv3.4 around the phosphorylation site of S15. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | KCNC4; Potassium voltage-gated channel subfamily C member 4; KSHIIIC; Voltage-gated potassium channel subunit Kv3.4 |
UniProt Protein Function: | Kv3.4: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.4/KCNC4 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p21 Cellular Component: plasma membrane Molecular Function:delayed rectifier potassium channel activity; potassium channel activity; voltage-gated potassium channel activity Biological Process: potassium ion transport; synaptic transmission |
NCBI Summary: | The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010] |
UniProt Code: | Q03721 |
NCBI GenInfo Identifier: | 66774206 |
NCBI Gene ID: | 3749 |
NCBI Accession: | Q03721.2 |
UniProt Secondary Accession: | Q03721,Q3MIM4, Q5TBI6, |
UniProt Related Accession: | Q03721 |
Molecular Weight: | 68,824 Da |
NCBI Full Name: | Potassium voltage-gated channel subfamily C member 4 |
NCBI Synonym Full Names: | potassium voltage-gated channel subfamily C member 4 |
NCBI Official Symbol: | KCNC4 |
NCBI Official Synonym Symbols: | KV3.4; C1orf30; KSHIIIC; HKSHIIIC |
NCBI Protein Information: | potassium voltage-gated channel subfamily C member 4 |
UniProt Protein Name: | Potassium voltage-gated channel subfamily C member 4 |
UniProt Synonym Protein Names: | KSHIIIC; Voltage-gated potassium channel subunit Kv3.4 |
Protein Family: | Potassium voltage-gated channel subfamily |
UniProt Gene Name: | KCNC4 |
UniProt Entry Name: | KCNC4_HUMAN |