Phospho-JUND (S255) Antibody (PACO05955)
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주문- SKU:
- PACO05955
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | Phospho-JUND (S255) Antibody (PACO05955) |
Antibody SKU: | PACO05955 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IP |
Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300, IP:2-5ug |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human Jun D around the phosphorylation site of S255. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | JUND; Transcription factor jun-D |
UniProt Protein Function: | JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. |
UniProt Protein Details: | Protein type:Transcription factor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleus; transcription factor complex Molecular Function:enzyme binding; ligand-dependent nuclear receptor binding; protein binding; transcription coactivator activity; transcription factor binding Biological Process: aging; cellular response to hormone stimulus; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; osteoblast development; positive regulation of cell differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to peptide hormone stimulus; response to radiation; transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013] |
UniProt Code: | P17535 |
NCBI GenInfo Identifier: | 229462969 |
NCBI Gene ID: | 3727 |
NCBI Accession: | P17535.3 |
UniProt Secondary Accession: | P17535,Q53EK9, |
UniProt Related Accession: | P17535 |
Molecular Weight: | 35,174 Da |
NCBI Full Name: | Transcription factor jun-D |
NCBI Synonym Full Names: | jun D proto-oncogene |
NCBI Official Symbol: | JUND |
NCBI Official Synonym Symbols: | AP-1 |
NCBI Protein Information: | transcription factor jun-D |
UniProt Protein Name: | Transcription factor jun-D |
Protein Family: | Transcription factor |
UniProt Gene Name: | JUND |
UniProt Entry Name: | JUND_HUMAN |