Phospho-IL9R (S519) Antibody (PACO04156)
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주문- SKU:
- PACO04156
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Phospho-IL9R (S519) Antibody |
Antibody SKU: | PACO04156 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from human IL-9R around the phosphorylation site of S519. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | IL9R; Interleukin-9 receptor; IL-9 receptor; IL-9R; CD antigen CD129 |
UniProt Protein Function: | IL9R: This is a receptor for interleukin-9. Belongs to the type I cytokine receptor family. Type 4 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, cytokine; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq28 and Yq12 Cellular Component: extracellular space; integral to plasma membrane Molecular Function:interleukin-9 binding; interleukin-9 receptor activity Biological Process: cell proliferation; signal transduction; positive regulation of cell growth |
NCBI Summary: | The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q01113 |
NCBI GenInfo Identifier: | 116242526 |
NCBI Gene ID: | 3581 |
NCBI Accession: | Q01113.3 |
UniProt Secondary Accession: | Q01113,Q14634, Q8WWU1, Q96TF0, B9ZVT0, |
UniProt Related Accession: | Q01113 |
Molecular Weight: | 521 |
NCBI Full Name: | Interleukin-9 receptor |
NCBI Synonym Full Names: | interleukin 9 receptor |
NCBI Official Symbol: | IL9R |
NCBI Official Synonym Symbols: | CD129; IL-9R |
NCBI Protein Information: | interleukin-9 receptor; IL-9 receptor |
UniProt Protein Name: | Interleukin-9 receptor |
UniProt Synonym Protein Names: | CD_antigen: CD129 |
Protein Family: | Interleukin-9 receptor |
UniProt Gene Name: | IL9R |
UniProt Entry Name: | IL9R_HUMAN |